Genetics, Cell or Developmental Biology
This lecture series honours Barbara McClintock, the pioneering corn geneticist James Watson called one of the three most important figures in biology in this century.
She obtained her PhD at Cornell University. At the time, there were few academic positions for women so she took a number of fellowships at Cornell, Caltech and later became Assistant Professor at the University of Missouri. She left Missouri because her advancement was blocked and, in 1941, she joined the Cold Spring Harbor Laboratories, remaining there for the rest of her life.
McClintock's incisive and brilliant cytogenetic studies of the 1930s let to the consolidation of the chromosome theory of inheritance, and to the discovery of the nucleolar organizer. From the 1940s onward, she discovered and characterized mobile genetic elements in maize, 40 years before their molecular basis was understood.
Among her many honors, Barbara McClintock was elected to the National Academy of Science in 1944, received the National Medal of Science in 1970, and was appointed a MacArthur Fellow in 1981. In 1983 she became only the third woman to receive an unshared Nobel Prize for her work on mobile elements. She died in 1992, universally admired for her extraordinary record of getting things right, based on observation and simple, elegant experiments that were years ahead of her time.
Previous Barbara McClintock Lecturers
|Year||Lecturer||Title of Seminar|
|2021||Iva Greenwald||LIN-12/Notch-mediated lateral specification in C. elegans gonadogenesis|
|2019||Victor Ambros||MicroRNA pathways and developmental timing in C. elegans|
|2018||Lawrence Zipursky||Mechanisms of neural circuit assembly: from cell recognition to neural activity|
|2017||Yishi Jin||Genetic dissection of synapse remodelling and maintenance|
|2013||Kang Shen||Extrinsic and intrinsic regulators of synapse formation in C. elegans|
|2012||Chris Q. Doe||Mechanism and function of spindle orientation in neural stem cells|
|2010||Riddle Symposium replaced McClintock lecture|
|2009||Sir John Sulston||Who owns science?|
|2008||Oliver Hobert||Gene regulatory mechanisms that control neuronal cell fate specifications in C. elegans|
|2007||Ulrich Tepass||Mechanisms of epithelial polarization and morphogenesis|
|2006||Pierre Drapeau||From autism to zebrafish: development of the motor system and systems biology of brain diseases|
|2005||Vincenzo Pirrotta||Polycomb silencing mechanisms and genomic programming|
|2004||Andy Fire||Cellular responses to foreign nucleic acids|
|2003||Alexander Mazo||The roles of histone modification in gene regulation|
|2002||Katherine Anderson||Drosophila toll signaling pathways in development and immunity|
|2001||Cynthia Kenyon||Aging in C. elegans|
|1999||Sean Carroll||Regulation of the body plan in development|
|1997||Ed M. Hedgecock||Genes that specify developmental age in C. elegans|
|1996||Elizabeth Blackburn||Telomeres and telomerase|
|1994||Corey Goodman||Molecular mechanisms generating neural specificity|
|1993||Helen M. Blau||Regulation of growth and differentiation by untranslated RNAs|
|1992||Paul Sternberg||Inductive signaling during C. elegans development|